This international research forum will once again bring together clinicians and established researchers in the fields of disc biology and biomedical engineering in a unique, stimulating environment. Participants, presenters, and faculty will have the opportunity to share their knowledge on basic, translational, and clinical research in the field of intervertebral disc and back/neck pain, focusing on today's knowledge ofdisc degeneration biology and biomechanics and its relationship to pain. These will be further complemented by sessions covering genetics, diagnostics, and disc/pain treatment modalities.