The Keystone Symposia meeting on Drug Resistance and Persistence in Tuberculosis aims to bring together basic and clinical researchers and public health experts from diverse backgrounds to explore the following:

1) the fundamental biology underlying genetic and phenotypic drug-resistance in TB; 

2) progress in expanding capacity in high-burden settings to perform drug susceptibility testing; 

3) identification of novel drug targets; 

4) innovative strategies for drug discovery; 

5) advances in developing multi-drug regimens that will be effective against currently drug-resistant as well as drug-sensitive strains of M. tuberculosis. 

Investigators from outside the TB field will be included to provide new perspectives and stimulate fresh approaches for tackling this global public health priority.